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If approved, Yselty will be the only GnRH antagonist addressing the needs of 3 distinct groups of women suffering from uterine fibroids, due to its flexible dose options: mg once daily for women with a contraindication to or who prefer to avoid hormonal add-back therapy ABT mg once daily with concomitant ABT for long-term use beyond 6 months mg once daily for short-term use, particularly when rapid reduction in fibroid and uterine volume is desired. The pooled Week 52 from the two studies showed that at Week 52, In PRIMROSE 2, following three months off-treatment, pain scores remained lower than baseline in all treatment arms, further supporting the durability of the Yselty treatment effect. For a ificant proportion of women, rapid and substantial shrinkage in uterine and fibroid volume is a primary treatment objective.

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ObsEva Announces Additional Phase 3 PRIMROSE 1 and 2 Study Confirming Sustained Efficacy and Continued Safety of linzagolix in the Treatment of Uterine Fibroids

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